Publications
Publications describing rDiff
- Accurate Detection of Differential RNA Processing, Drewe P, Stegle O, Hartmann L, Kahles A, Bohnert R, Wachter A, Borgward K, Rätsch G, Nucl. Acids Res. (2013) 41 (10): 5189-5198, online access
Supplemental data
Dataset 1 (small biological variance) Dataset 2 (large biological variance) Bam Files:
condition_A_replicate_1.bam
condition_A_replicate_2.bam
condition_B_replicate_1.bam
condition_B_replicate_2.bamBam Files:
condition_A_replicate_1_large_var.bam
condition_A_replicate_2_large_var.bam
condition_B_replicate_1_large_var.bam
condition_B_replicate_2_large_var.bamGenome annotation with label:
genes_label.matGenome annotation with label:
genes_label_large_var.mat
- Statistical Tests for Detecting Differential RNA-Transcript Expression from Read Counts, Stegle O, Drewe P, Bohnert R,Borgwardt K , Rätsch G, Nature Precedings, 2012 online access
rDiff use cases
- Polypyrimidine tract binding protein homologs from Arabidopsis are key regulators of alternative splicing with implications in fundamental developmental processes, Rühl C, Stauffer E, Kahles A, Wagner G, Drechsel G, Rätsch G, Wachter A, Plant Cell, 2012 Nov;24(11):4360-75 online access